In volunteers with a single dose of sildenafil 100mg in doses up to 100 mg showed no clinically significant ECG abnormalities. The maximum mean reduction of systolic pressure in a horizontal position after oral administration of a dose of 100 mg was 8.34 mm Hg in the field. The corresponding to the diastolic pressure in a horizontal position 5.3 mm of mercury. of art. Lower than normal, but a short time, lowers blood pressure in patients taking nitrates.
In studies of sildenafil 100mg showed a systemic vasodilatory action that led to a temporary decrease in blood pressure. This effect is negligible, or will not lead to a result in most patients. Yet the appointment of the doctor sildenafil 100mg carefully weigh the risk of adverse effects of vasodilator drug in patients with certain underlying medical conditions, especially in the context of sexual activity. Increased sensitivity to vasodilators observed in patients with obstruction of the left ventricle (aortic stenosis, obstructive hypertrophic cardiomyopathy), and multiple system atrophy side effects reported in isolated cases and appear to be severely impaired autonomic control of blood pressure.
Viagra 100 mg once daily after oral administration to patients with severe heart disease (70% stenosis of at least one coronary artery) reduces the average performance of the systolic and diastolic blood pressure at rest 7% and 6% compared to baseline. The mean pulmonary artery systolic pressure decreased by 9%. sildenafil 100mg 100mg has no effect on cardiac output and blood flow in stenosed coronary arteries as a result of the improvement (13%) adenosine-stimulated blood flow reserve (with and without coronary artery stenosis).
Effects on the mechanisms of the ability to drive and monitor
In light of the drug Viagra � has a negative effect on driving or other technical measures are not followed. For while the medicine the blood pressure, hromatopsii development, reduction of blurred vision, the individual effects of the drug in these circumstances, especially in the beginning of treatment and when changing the dose.
In the single dose of the drug at a dose of 800 mg of adverse reactions were similar to those taking sildenafil 100mg 100mg at lower doses, but was more common.
Treatment: If necessary, symptomatic treatment. Hemodialysis does not accelerate clearance of sildenafil 100mg 100mg, which binds avidly to date to plasma proteins and is excreted in the urine.
General Holiday pharmacies
The drug is a prescription drug.
Conditions for storage
List B. The drug should be stored out of reach of children, in a dry place at temperatures below 30 � C. Shelf life - 5 years.
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